A generalized fixed drug eruption associated with mycophenolate

FDE: fixed drug eruption INTRODUCTION Mycophenolate is a reversible inhibitor of inosine monophosphate dehydrogenase, which plays an important role in the production of DNA. This drug is commonly used in several autoimmune and inflammatory conditions, including connective tissue diseases, immunobullous disease, and atopic dermatitis, and in the setting of organ transplantation. Mycophenolate is considered first-line therapy in many patients because of its relatively minimal side effect profile when compared with other immunosuppressive agents. Most common side effects include diarrhea, gastrointestinal distress, peripheral edema, and high blood pressure. Less common side effects include pancytopenias and risk of infection. Given the overall prevalence of mycophenolate use, we present a rare case of a generalized fixed drug eruption caused by mycophenolate.